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American Society of Microbiology ABMM Sample Questions (Q17-Q22):

NEW QUESTION # 17
A patient with HIV infection and a CD4+ T-cell count below 100 cells/µL presents with headache, fever, and altered mental status. CSF analysis reveals elevated protein and low glucose. India ink stain is negative.
Cryptococcal antigen test of the CSF is positive. The MOST appropriate initial treatment is:

A. Caspofungin
B. Voriconazole
C. Amphotericin B and flucytosine
D. Fluconazole

Answer: C

NEW QUESTION # 18
A research laboratory is investigating the mechanism of action of a novel antiviral compound. In vitro studies demonstrate that the compound effectively inhibits the replication of a specific enveloped RNA virus. Further analysis reveals that the compound does not interfere with viral entry, genome replication, or protein synthesis. However, electron microscopy of infected cells treated with the compound shows an accumulation of viral glycoproteins within the endoplasmic reticulum and Golgi apparatus, with a significant reduction in the release of infectious virions. The MOST likely target of this antiviral compound is:

A. Host cell membrane fusion machinery
B. Viral glycoprotein trafficking and maturation
C. Viral RNA-dependent RNA polymerase
D. Viral protease responsible for polyprotein cleavage

Answer: B

NEW QUESTION # 19
A patient with a history of neutropenia develops a severe sinus infection. Tissue biopsy reveals broad, ribbon- like, non-septate hyphae with right-angle branching. The MOST likely causative organism belongs to the order:

A. Mucorales
B. Eurotiales
C. Aspergillales
D. Onygenales

Answer: A

NEW QUESTION # 20
A research laboratory is investigating the mechanisms of antiviral drug resistance. They are studying a herpes simplex virus strain that has developed resistance to acyclovir. The MOST common mechanism of acyclovir resistance in HSV involves mutations in the gene encoding:

A. Viral protease
B. Viral thymidine kinase
C. Viral DNA polymerase
D. Viral glycoprotein D

Answer: B

NEW QUESTION # 21
A patient with a history of solid organ transplantation develops a severe respiratory illness. Bronchoalveolar lavage fluid is positive for cytomegalovirus (CMV) DNA by PCR, and cytological examination reveals characteristic "owl's eye" inclusions in enlarged cells. The MOST appropriate management strategy for this patient would include:

A. Initiation of broad-spectrum antibiotics to cover potential bacterial coinfections.
B. Administration of corticosteroids to reduce inflammation.
C. Treatment with antiviral agents such as ganciclovir or valganciclovir.
D. Supportive care and monitoring for spontaneous resolution.

Answer: C

NEW QUESTION # 22
......

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2026 100% Free ABMM–Excellent 100% Free Certification Exam Dumps | Passing ABMM Score

Free PDF Quiz 2026 American Society of Microbiology ABMM: ABMM Pass-Sure Certification Exam Dumps

American Society of Microbiology ABMM Sample Questions (Q17-Q22):

ABMM Test Questions: ABMM & ABMM Actual Test & ABMM Exam Simulation

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